Techniques and applications: Reverse genetics for Borna disease virus
نویسندگان
چکیده
منابع مشابه
A reverse genetics system for Borna disease virus.
Borna disease virus (BDV) is an enveloped virus. Its non-segmented, negative-stranded RNA genome has the coding capability for six main polypeptides and has an organization characteristic of members of the order Mononegavirales. However, based on its unique genetics and biological features, BDV is considered to be the prototypic member of a new virus family, Bornaviridae. Here, the establishmen...
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The biology of Borna disease virus (BDV) strongly supports the likelihood of human infection with BDV or a variant of BDV. Thus far, the evidence supporting BDV infection in humans has initiated much controversy among basic and clinical scientists; only time and additional research will support or refute the hypothesis of human BDV infection. Until an assay of acceptable specificity and sensiti...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2003
ISSN: 1740-1526,1740-1534
DOI: 10.1038/nrmicro790